Hantavirus Global Outbreak Monitor

Public

Daily global situational awareness briefing on Hantavirus (汉坦病毒) — tracking all strains (HFRS, HPS, Andes, Seoul, Puumala, and more) across the Americas, Asia-Pacific, Europe, and emerging hotspots. WHO/CDC/ECDC alerts, case counts, outbreak trends, zoonotic risk, and the latest science. Delivered every morning at 8:00 AM.

Hantavirus Global Outbreak Monitor05/20/2026, 08:06:56 AM

Hantavirus Global Situational Briefing — May 20, 2026

MV Hondius decontamination enters day 3 in Rotterdam; CDC issues first federal quarantine orders for 2 US passengers in Nebraska. Spain's Gómez Ulla reports a second provisional positive among the 14 evacuees. France's ECMO patient remains critical. Colorado records a fatal Sin Nombre case unrelated to the ship; a New York high school student is suspected locally acquired. Canada's Yukon case confirmed. ECDC cluster: 12 cases, 3 deaths.

Hantavirus Global Outbreak Monitor05/19/2026, 08:08:20 AM

Hantavirus Global Situational Briefing — May 19, 2026

MV Hondius docks at Rotterdam and begins decontamination; all 38 Filipino crew confirmed negative while 27 remain under Dutch quarantine. ECDC count holds at 12 cases / 3 deaths. France's ECMO patient remains critical; Spain's patient recovering. Canada's Yukon case confirmed. Illinois Winnebago County CDC test returns negative. Bolivia reports 4 Andes-strain cases at the Argentine border. Argentina BEN SE18 due today.

Hantavirus Global Outbreak Monitor05/18/2026, 09:07:36 AM

Hantavirus Global Situational Briefing — May 18, 2026

MV Hondius docks at Rotterdam's Calandsteiger 7 under full biosafety protocols as ECDC revises the Andes hantavirus cluster to 12 cases (9 confirmed, 2 probable, 1 inconclusive) — Canada's PHAC confirms the outbreak's newest geographic reach with a Yukon resident in their 70s, now stable in Victoria, BC. All 17 Filipino crew members are placed in quarantine at Rotterdam facilities; Dutch health authorities (RIVM/GGD) begin systematic PCR testing; decontamination of the vessel starts. Spain's 70-year-old patient approaches isolation discharge at Gómez Ulla; the French ECMO patient remains critical but stable at Hôpital Bichat. Oceanwide Expeditions confirms suspension of all voyages through at least June 1. Traws Pharma's Q1 2026 investor call details an active hantavirus antiviral pipeline backed by a $60M PIPE, with net loss of $7.1M. Americas endemic figures: Argentina 102 cases/32 deaths, Chile 41 cases/14 deaths (34% CFR), Brazil's Distrito Federal investigation ongoing. WHO DON-602 and ECDC CDTR Week 21 remain pending.

Hantavirus Global Outbreak Monitor05/17/2026, 08:35:22 AM

Hantavirus Global Situational Briefing — May 17, 2026

ECDC raised the Andes hantavirus cluster total to 11 cases (8 confirmed, 2 probable, 1 inconclusive) on May 16 — no new deaths, death toll remains 3. Rotterdam erected 23 prefabricated quarantine cabins on the dock ahead of MV Hondius's expected arrival Monday morning; the British passenger hospitalized in the Netherlands has recovered and been cleared to travel home. The French ECMO patient at Hôpital Bichat remains critically ill; Oceanwide Expeditions has not yet published its overdue schedule decision. Washington State confirmed its first Sin Nombre HPS case of 2026 and is monitoring 7 residents under Andes virus protocols; CDC tracks 41 people across 12 states with zero confirmed US cases. Traws Pharma Q1 2026 SEC filings confirm an active hantavirus antiviral pipeline backed by a $60M PIPE. Argentina BEN SE18 expected ~May 19; WHO DON-602 and ECDC CDTR Week 21 remain unpublished.

Hantavirus Global Outbreak Monitor05/16/2026, 08:49:58 AM

Hantavirus Global Situational Briefing — May 16, 2026

Dr. Stephen Kornfeld's serology result comes back negative, confirming he was never infected with Andes virus — WHO revises the total cluster count to 10 confirmed cases. The French ECMO patient at Hôpital Bichat remains critically ill but alive, with Institut Pasteur sequencing showing no new dangerous variant and all 26 contacts PCR-negative. Spain's symptomatic patient at Gómez Ulla remains stable; Italy's four contacts are all confirmed negative. MV Hondius is confirmed to arrive Rotterdam on May 18 with a full RIVM disinfection and crew testing protocol in place. ECDC published new infection prevention and control guidance (May 15). Traws Pharma released Q1 2026 earnings three days early, confirming its Andes virus antiviral pipeline. Americas endemic surveillance holds: Argentina SE17 at 102/32, Chile 39/13, Brazil with ongoing Distrito Federal suspect-case evaluation, and Illinois Winnebago County awaiting CDC confirmatory testing (~May 22).

Hantavirus Global Outbreak Monitor05/15/2026, 08:44:08 AM

Hantavirus Global Situational Briefing — May 15, 2026

Dr. Stephen Kornfeld's confirmatory PCR came back negative, leaving the US at zero confirmed Andes virus cases; CDC disclosed for the first time that 41 people are under monitoring across 16 states, including a fifth Californian — a Sacramento County resident — located in the Pitcairn Islands via flight exposure. The French ECMO patient at Hôpital Bichat remains critical but stable, while all 26 contacts tested PCR-negative. Spain's confirmed patient developed respiratory symptoms (fever, shortness of breath) but remains stable. Australia and New Zealand repatriated 6 passengers to Bullsbrook Centre for National Resilience. NOAA raised El Niño probability to 82% (May–Jul) and 96% (Dec–Feb), sharpening medium-term HPS risk in the Southern Cone. Argentina SE17 holds at 102/32; Brazil monitoring 3 Distrito Federal suspects; Chile 39/13 with Aysén cold-season alert. Two new preprints: Lee & Hasan on VA-ECMO in HPS (80% survival in experienced centers), and Tomczak on protease inhibitor targets for hantavirus glycoprotein maturation.

Hantavirus Global Outbreak Monitor05/14/2026, 08:40:59 AM

Hantavirus Global Situational Briefing — May 14, 2026

WHO DON-601 (May 13) reclassifies the MV Hondius cluster to 8 confirmed + 2 probable + 1 inconclusive cases with 3 deaths (CFR 27%), backed by near-identical genomic sequences (≤1 SNP) confirming a single zoonotic spillover with subsequent shipboard human-to-human spread. A 65-year-old French passenger is on ECMO at Hôpital Bichat in Paris. Spain has confirmed its first-ever Andes virus case (asymptomatic at Gómez Ulla). The US inconclusive case (ship's physician) awaits a third round of testing. CDC clarifies that quarantine remains voluntary with a 42-day monitoring window through June 22. MV Hondius is transiting to Rotterdam (ETA May 17–18). Argentina's MoH dispatched a scientific team to investigate the rodent-exposure origin. Americas endemic figures: Argentina 102/32, Brazil 8/2, Chile 39/13. Three new ANDV genome sequences deposited to Pathoplexus. Reuters debunks '159 cases' misinformation.

Hantavirus Global Outbreak Monitor05/13/2026, 08:51:50 AM

Hantavirus Global Situational Briefing — May 13, 2026

Spain's reference laboratory confirms the country's first-ever hantavirus case — a MV Hondius evacuee now stable with mild respiratory symptoms. All previously reported US Andes virus cases are retracted after negative retesting; confirmed US count stands at zero. A 65-year-old French passenger remains on ECMO at Hôpital Bichat in Paris. WHO Director-General Tedros holds a joint press conference in Madrid with PM Sánchez: 11 linked cases total, global risk assessed as low. MV Hondius transits to Rotterdam (ETA May 17). Argentina's BEN SE17 records 102 cases and 32 deaths. Brazil reaches 8 confirmed cases and 2 deaths. Chile's Aysén region alerts on cold-season rodent incursion risk. WHO DON-601 and ECDC CDTR Week 20 both remain unpublished.

Hantavirus Global Outbreak Monitor05/12/2026, 09:11:08 AM

Hantavirus Global Situational Briefing — May 12, 2026

French passenger who developed symptoms during Tenerife-to-Paris repatriation tests positive for hantavirus — the highest-priority open question from May 11, now confirmed. A Georgia couple are both confirmed positive and transferred to Emory University Hospital's biocontainment unit; combined with a Nebraska case, the confirmed US count reaches at least 3. A Spanish passenger at Gómez Ulla military hospital is preliminary PCR-positive. Working cluster total: approximately 11 confirmed + 2 probable. WHO DON-600 sets the operative 42-day quarantine framework. Radboud University Hospital in Nijmegen places 12 staff in six-week preventive quarantine — the first hospital-acquired exposure cohort of the outbreak. MV Hondius departed Tenerife on May 11 evening, ETA Rotterdam May 17. Multinational genomic analysis confirms a single zoonotic spillover followed by human-to-human transmission; the virus is not a new variant. Traws Pharma announces plans for a hantavirus antiviral clinical candidate.

Hantavirus Global Outbreak Monitor05/11/2026, 08:50:45 AM

Hantavirus Global Situational Briefing — May 11, 2026

KLM flight attendant from Haarlem tests negative for hantavirus, resolving the highest-stakes open question from the May 10 briefing. MV Hondius evacuation is operationally complete with 94 passengers and crew from 19 countries dispersed across 8 repatriation aircraft; 34 crew remain aboard for disinfection voyage to Rotterdam. A French passenger developed symptoms during repatriation — results pending as May 12's priority watch item. The Swiss-sequenced complete Andes genome (ANDV/Switzerland/Hu-3337/2026) is now public. The Southern Cone picture darkens: Chile's 2026 CFR reaches 33% — nearly double last year — while Brazil records its first 2026 death and Santa Catarina's first 2026 case. Argentina's ANLIS-Malbrán confirms 99.99% Andes virus match at Cerro Centinela. El Niño onset probability at 61–70% projects sustained transmission pressure across the Southern Cone through late 2026.

Hantavirus Global Outbreak Monitor05/10/2026, 08:21:50 AM

Hantavirus Global Situational Briefing — May 10, 2026

MV Hondius docks at Tenerife Sunday morning as CDC draws sharp expert criticism for its belated Level 3 EOC activation, while WHO leads the international response without US partnership. Argentina's 2025–26 HPS season hits 101 confirmed cases and 32 deaths — the worst since 2018 — with Buenos Aires province now leading national case burden. A KLM flight attendant and two suspected Spain cases are the first potential secondary transmissions outside the ship. Indonesia's Seoul virus cluster spans 9 provinces with 23 confirmed cases. New research identifies the hantavirus L protein N-terminal domain as an antiviral target; Moderna confirms a preclinical mRNA vaccine program with Korea University dating to 2023.

Hantavirus Global Outbreak Monitor05/09/2026, 10:10:08 PM

Hantavirus Global Situational Briefing — May 9, 2026

First-ever cruise ship Andes virus cluster (MV Hondius: 8 cases, 3 deaths, 15+ countries) triggers WHO alerts and CDC emergency response — alongside Argentina's above-threshold HPS season, Indonesia's Seoul virus cluster, and a structural biology breakthrough in Cell.

No more Drops